High‐Performance Magnetic FePt (L1 <sub>0</sub> ) Surface Microrollers Towards Medical Imaging‐Guided Endovascular Delivery Applications

نویسندگان

چکیده

Controlled microrobotic navigation in the vascular system can revolutionize minimally invasive medical applications, such as targeted drug and gene delivery. Magnetically controlled surface microrollers have emerged a promising platform for circulatory system. Locomotion of micrororollers strong flow velocities is highly challenging task, which requires magnetic materials having actuation properties while being biocompatible. The L10-FePt coating achieve requirements. Therefore, has been integrated into 8 µm-diameter investigated potential from locomotion performance, biocompatibility, imaging perspectives. FePt significantly advanced performance biocompatibility compared to previously used material, nickel. also allowed multimodal resonance photoacoustic ex vivo settings without additional contrast agents. Finally, FePt-coated showed upstream ability against 4.5 cm s−1 average velocity with real-time imaging, demonstrating control future applications. Overall, conceived key material image-guided propulsion perform interventions.

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ژورنال

عنوان ژورنال: Advanced Functional Materials

سال: 2021

ISSN: ['1616-301X', '1616-3028']

DOI: https://doi.org/10.1002/adfm.202109741